Michigan Technological University · ChemistryThe Fluorescent Insight Lab
Haiying Liu · Houghton, Michigan
Research Focus
Dr. Haiying Liu's lab focuses on creating advanced fluorescent probes that can detect changes in viscosity and protein aggregation within live cells. These innovative probes use near-infrared imaging to provide clear visual assessments of critical cellular environments, helping to monitor diseases like Alzheimer's and cancer more effectively. By improving the accuracy of these detections, their research aims to enhance early diagnosis and treatment monitoring, making significant impacts in cellular imaging and disease diagnostics.
fluorescent probesnear-infrared imagingviscosity sensingprotein aggregationneurodegenerative diseasescancer diagnosticsBODIPY dyesself-calibrating systemscell permeability
Research Aims
5AIM 01Develop advanced fluorescent probes for viscosity detection in live cells.
AIM 02Create self-calibrating ratiometric systems to improve measurement accuracy.
AIM 03Monitor protein misfolding and aggregation related to neurodegenerative diseases.
AIM 04Investigate the effects of environmental factors on protein dynamics.
AIM 05Enhance the understanding of cellular microenvironments relevant to cancer.
Skills the Lab Values
fluorescent imagingcell culture techniquesmolecular dynamics simulationsnear-infrared optical imagingratiometric imagingprotein aggregation assayschemical intervention studiesdata analysis using computational methodsorganic synthesis of dyes
Output against the department
Publications379top 29% of dept.62nd of 216
this lab
most publishedleast published
Citations13ktop 38% of dept.83rd of 216
this lab
most citedleast cited
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