Boston University · BiologyThe Polyphosphate Project
Markus Bosmann · Boston, Massachusetts
Research Focus
Dr. Markus Bosmann's lab focuses on understanding how bacterial polyphosphates influence immune responses in the intestines, especially in relation to inflammatory bowel disease (IBD). They study how these bacterial metabolites affect immune cell interactions and contribute to the severity of gut inflammation. This research aims to uncover new therapeutic strategies for IBD by examining the gut microbiota's role in immune system regulation.
bacterial polyphosphatesinflammatory bowel diseaseintestinal immunityimmune cell signalingmetagenomics
Research Aims
3AIM 01Characterize the modulation of intestinal immune cell networks by bacterial polyphosphates.
AIM 02Investigate the effects of polyphosphates on IL-27 release and JAK/STAT signaling in immune cells.
AIM 03Study the role of polyphosphates in human diseases like inflammatory bowel disease.
Skills the Lab Values
cell cultureimmunophenotypinganimal modelsJAK/STAT signaling assaysmetagenomic analysis
Output against the department
Publications128bottom 46% of dept.556th of 1,033
this lab
most publishedleast published
Citations4.5kbottom 35% of dept.671st of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.