University of Toledo · BiologyLiu Exosome Lab
Shi-He Liu · Toledo, Ohio
Research Focus
Dr. Shi-He Liu's lab at the University of Toledo focuses on developing advanced delivery systems for targeted cancer therapies, especially for pancreatic cancer. They are engineering exosomes, which are tiny vesicles that can carry drugs or genes to specific cells. The goal is to improve the accuracy and effectiveness of cancer treatments while reducing side effects. Their innovative approaches may lead to significant breakthroughs in cancer medicine.
exosome engineeringpancreatic cancerdrug deliverygene therapytumor targetingnanocarriersbiocompatibilitytherapeutic targetingcancer therapy
Research Aims
3AIM 01Evaluate the targeting capabilities of engineered exosomes in pancreatic cancer models.
AIM 02Validate the effectiveness of exosomes carrying chemotherapy in mouse models of pancreatic cancer.
AIM 03Optimize exosome engineering for personalized cancer therapies.
Skills the Lab Values
exosome isolationpeptide engineeringin vitro tumor modelsanimal modelschemotherapy testingbiochemical assays3D spheroid culturemolecular biology techniqueslipid formulation
Output against the department
Publications37bottom 6% of dept.968th of 1,033
this lab
most publishedleast published
Citations568bottom 2% of dept.1,009th of 1,033
this lab
most citedleast cited
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