University of New Mexico-Main Campus · BiologyNaik Lab
Jay S Naik · Albuquerque, New Mexico
Research Focus
Dr. Jay Naik's lab focuses on understanding how hydrogen sulfide (H2S), a compound naturally produced by our cells, helps regulate blood pressure and blood flow, especially in relation to cardiovascular diseases. The lab explores how the content of cholesterol in endothelial cells affects their ability to use H2S for vasodilation, which is crucial for maintaining healthy blood circulation. This research aims to uncover new therapeutic targets to treat cardiovascular conditions like hypertension and stroke.
H2Svascular functionendothelial cellscholesterolvasodilationcardiovascular diseaseshydrogen sulfideblood pressure regulationmembrane cholesterol
Research Aims
2AIM 01Determine the mechanisms leading to differences in membrane cholesterol content between large and small arteries.
AIM 02Identify how membrane cholesterol regulates H2S signaling in endothelial cells.
Skills the Lab Values
cell culturein vitro experimentationanimal modelsmolecular biology techniquesWestern blotspectrophotometryimmunohistochemistrygene expression analysislipid extraction
Output against the department
Publications112bottom 39% of dept.625th of 1,033
this lab
most publishedleast published
Citations1.2kbottom 7% of dept.965th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.