University of California-Berkeley · BiochemistryBrar Lab
Gloria Ann Brar · Berkeley, California
Research Focus
Dr. Gloria Ann Brar's lab focuses on understanding how cells rejuvenate their protein components during the formation of gametes, which are essential for sexual reproduction. By studying the simple budding yeast, they aim to identify the key proteins that are reset to maintain their youthfulness, even when derived from older cells. This research could provide insights into aging and new strategies to combat age-related cellular damage.
gametogenesisproteome remodelingcell agingyeast modelprotein quality control
Research Aims
5AIM 01Identify key proteins involved in gamete rejuvenation.
AIM 02Characterize the proteomic changes during gametogenesis.
AIM 03Investigate the mechanisms of protein degradation and aggregation.
AIM 04Analyze the role of housekeeping proteins in cell vitality.
AIM 05Explore strategies to enhance cellular youthfulness and combat aging.
Skills the Lab Values
proteomicsmass spectrometrycell culturemicroscopybiochemical assays
Output against the department
Publications77bottom 15% of dept.340th of 402
this lab
most publishedleast published
Citations9.7ktop 50% of dept.200th of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.