Johns Hopkins University · BiologyAndrew Proteomics Lab
Deborah J Andrew · Baltimore, Maryland
Research Focus
Dr. Deborah J Andrew's research lab focuses on understanding how specific proteins influence the formation and function of organs using the Drosophila salivary gland as a model. By investigating the roles of transcription factors in organ development, the lab aims to uncover the mechanisms that guide tissue morphogenesis and physiological specialization. This research has implications for understanding human organ development and diseases such as cancer.
FoxA proteinsDrosophilasalivary glandtranscription factorstissue morphogenesis
Research Aims
3AIM 01Investigate the interaction of Fork head with other transcription factors to regulate salivary gland secretome expression.
AIM 02Characterize the protein partners and downstream targets involved in morphological changes of the salivary gland.
AIM 03Determine the role of specific morphogenetic targets in coordinating tissue remodeling and architecture.
Skills the Lab Values
genetic manipulationDrosophila breedingmolecular cloninggene expression analysisimmunostainingmicroscopyRNA interferenceprotein assays
Output against the department
Publications135bottom 48% of dept.529th of 1,033
this lab
most publishedleast published
Citations5.9kbottom 43% of dept.593rd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.