Harvard University · Microbiology & ImmunologyVon Andrian Lab
Ulrich H Von Andrian · Cambridge, Massachusetts
Research Focus
Dr. Ulrich H. Von Andrian's lab at Harvard Medical School focuses on understanding how the immune system responds to infections, particularly in the nasal mucosa, which is often the first line of defense against airborne pathogens. The lab uses advanced microscopy techniques to study the dynamic behavior of immune cells like neutrophils and how they interact within different regions of the nasal cavity. Additionally, the lab explores the mechanisms behind lymphocyte trafficking in the body, investigating how certain blood vessels help immune cells reach their infection sites. This research has important implications for improving vaccine efficacy and developing treatments for diseases related to inflammation and cancer.
neutrophil dynamicsnasal mucosaimmune responselymphocyte traffickinghigh endothelial venuleschronic inflammationimmunotherapycytokine signalingmicrobiologyvirology
Research Aims
4AIM 01Define the origin and migratory properties of nasal neutrophil subsets.
AIM 02Characterize the function of each neutrophil subset in health and disease.
AIM 03Investigate how endothelial signaling affects the formation of high endothelial venules.
AIM 04Explore the role of specific cytokines in lymphocyte trafficking and endothelial cell reprogramming.
Skills the Lab Values
intravital microscopyflow cytometrymouse modelscell cultureimmunohistochemistrymolecular biology techniquesgene expression analysistissue sectioninganimal handlingdata analysis in immunology
Output against the department
Publications427top 8% of dept.37th of 486
this lab
most publishedleast published
Citations58ktop 3% of dept.14th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.