North Carolina State University at Raleigh · EngineeringFreytes Lab
Donald O Freytes · Raleigh, North Carolina
Research Focus
Dr. Donald O Freytes' lab at NC State University focuses on developing a new, non-invasive treatment for voice disorders that affect millions of Americans. The lab studies a special extract from vocal folds, which has shown promise in healing injuries and reducing scarring without needing surgery. Their work includes testing how this extract works at a molecular level and evaluating its safety and effectiveness in animal models.
vocal fold healingnon-invasive therapyfibrosislamina propriawound healinganimal modelsaerosol deliverytherapeutic propertiespublic health
Research Aims
3AIM 01Investigate the anti-fibrotic and anti-microbial properties of Vocal Fold Lamina Propria extract.
AIM 02Assess the efficacy of VFLPx in promoting wound healing in a rabbit model of vocal fold injury.
AIM 03Evaluate the safety of nebulized VFLPx in a rat model focusing on lung function.
Skills the Lab Values
proteomic analysisanimal model experimentationaerosol delivery techniquesmolecular biology techniquesinjection methodologieshistological assessmentnebulizer usebiomechanics studiesdata collection and analysis
Output against the department
Publications85bottom 18% of dept.227th of 278
this lab
most publishedleast published
Citations8.2ktop 45% of dept.126th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.