Icahn School of Medicine at Mount Sinai · Biomedical EngineeringThe NeuroPASC Initiative
Alan C Seifert · New York, New York
Research Focus
Dr. Alan C Seifert's lab investigates how COVID-19 affects the brain, particularly in patients who experience ongoing neurological issues after recovering from the virus. This condition, known as neuroPASC, can include symptoms like memory problems, fatigue, and mood disorders. The lab uses advanced MRI techniques to study brain damage and aims to uncover the underlying mechanisms of this syndrome to aid in developing targeted treatments.
COVID-19neuroPASCbrain imagingMRIinflammationneuropsychologyblood-brain barrierhistologyneurological symptoms
Research Aims
5AIM 01Investigate the mechanisms of brain injury caused by SARS-CoV-2 infection.
AIM 02Compare neuroimaging and histological findings between neuroPASC-positive and control subjects.
AIM 03Assess changes in neuroimaging findings over time in neuroPASC patients.
AIM 04Establish biomarkers that could signal the effectiveness of potential treatments for neuroPASC.
AIM 05Utilize advanced imaging techniques to better understand the impact of COVID-19 on the central nervous system.
Skills the Lab Values
Quantitative MRIHistological analysisNeuropsychological testingSample collectionData analysisComputational imaging techniquesEx vivo imagingBrain tissue stainingStatistical modeling
Output against the department
Publications86bottom 13% of dept.516th of 595
this lab
most publishedleast published
Citations2.2kbottom 16% of dept.498th of 595
this lab
most citedleast cited
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