University of Pittsburgh-Pittsburgh Campus · Biomedical EngineeringThe Silk Regeneration Lab
David Alan Vorp · Pittsburgh, Pennsylvania
Research Focus
David Vorp's lab focuses on innovative approaches to regenerative medicine, using advanced techniques to attach extracellular vesicles (EVs) to biomaterials like silk for tissue repair. Their research aims to harness these natural signals from stem cells to improve healing and support the development of new treatments for chronic wounds and other medical applications. By collaborating with industry partners, they aim to make these technologies more accessible for clinical use.
extracellular vesiclesregenerative medicinebiomaterialssilk fibrointissue engineering
Research Aims
4AIM 01Demonstrate Az-EV immobilization to silk fibroin-based materials.
AIM 02Validate MSC-mimicking effects of immobilized Az-EVs in vitro.
AIM 03Test regenerative effects of Az-EVs in a mouse chronic wound healing model.
AIM 04Evaluate regenerative potential of Az-EVs in a rat tissue engineered vascular graft model.
Skills the Lab Values
click chemistrycell cultureanimal modelswound healing assaysbiomaterials characterizationmicroscopystem cell isolationprotein analysisin vitro testingexperimental design
Output against the department
Publications4bottom 1% of dept.587th of 595
this lab
most publishedleast published
Citations3bottom 1% of dept.588th of 595
this lab
most citedleast cited
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