Indiana University-Purdue University-Indianapolis · NeuroscienceDage Biomarkers Lab
Jeffrey Dage · Indianapolis, Indiana
Research Focus
Dr. Jeffrey Dage's lab focuses on finding new biomarkers for Alzheimer's disease (AD) and related conditions like progressive supranuclear palsy (PSP). By studying different forms of the tau protein in the blood, the lab aims to improve early diagnosis and understanding of these diseases. Their work involves advanced techniques to analyze blood samples from clinical trials, contributing to better detection of tau-related disorders.
tau proteinAlzheimer's diseasebiomarkersblood-based assaysprogressive supranuclear palsy
Research Aims
5AIM 01Identify novel tau proteoforms in blood samples.
AIM 02Differentiate healthy volunteers from AD and PSP patients using new biomarkers.
AIM 03Explore the impact of tau immunotherapy on biomarker detection.
AIM 04Provide resources for future research on tauopathies.
AIM 05Facilitate early diagnosis of Alzheimer's disease and related conditions.
Skills the Lab Values
immunoprecipitationmass spectrometrybiofluid samplingclinical trial analysisbiomarker discovery
Output against the department
Publications231top 31% of dept.211th of 671
this lab
most publishedleast published
Citations15ktop 26% of dept.175th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.