Johns Hopkins University · Biomedical EngineeringCerebral Dynamics Lab
Hanzhang Lu · Baltimore, Maryland
Research Focus
The research lab led by Hanzhang Lu at Johns Hopkins University focuses on understanding the vascular contributions to cognitive impairment and dementia, particularly small-vessel-related conditions. They work on developing and validating biomarkers that can help in the diagnosis and treatment of various types of dementia, including Alzheimer's disease. Their pioneering work includes using advanced MRI techniques to measure brain physiology, aiming to improve patient care through better diagnostic tools.
biomarkerscognitive impairmentvascular dementiaMRIAlzheimer's diseasecerebrovascular reactivitylongitudinal studiesclinical trials
Research Aims
4AIM 01Develop biomarkers for vascular cognitive impairment and dementia
AIM 02Validate cerebrovascular reactivity (CVR) in clinical settings
AIM 03Conduct longitudinal studies to track changes in cognitive function
AIM 04Establish protocols for multi-site clinical trials
Skills the Lab Values
MRI imagingbiomarker analysisclinical trial methodologieslongitudinal data collectiondata managementneuropsychological assessmentsbiofluid analysisstatistical analysis
Output against the department
Publications500top 16% of dept.95th of 595
this lab
most publishedleast published
Citations23ktop 15% of dept.87th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.