Icahn School of Medicine at Mount Sinai · NeuroscienceThe Opioid Pathways Lab
Yasmin L. Hurd · New York, New York
Research Focus
Dr. Yasmin L. Hurd's lab focuses on understanding opioid use disorder, particularly how heroin affects the brain at a molecular level. The team combines human and animal studies to explore the neurobiological changes caused by opioids, aiming to identify new treatment options for addiction that avoid the risks of traditional opioid-based medications. By investigating specific pathways involved in addiction, they hope to develop targeted therapies that can better aid individuals struggling with opioid dependence.
opioid use disorderheroin addictionneurobiologyFYNglutamatergic signalingepigeneticstau phosphorylationpharmacotherapyaddiction treatmentbrain research
Research Aims
4AIM 01Investigate the molecular signature of FYN-related networks associated with heroin abuse.
AIM 02Characterize cell-specific alterations mediated by Fyn in addiction behaviors.
AIM 03Explore the neurobiological impact of opioids on mesocorticolimbic brain regions.
AIM 04Develop therapeutic targets for opioid addiction based on FYN expression and activity.
Skills the Lab Values
RNA sequencingcell cultureanimal modelsmolecular profilingin situ hybridizationfluorescence microscopydata analysisprotein phosphorylation techniquesbehavioral assayspharmacological interventions
Output against the department
Publications335top 20% of dept.134th of 671
this lab
most publishedleast published
Citations21ktop 20% of dept.132nd of 671
this lab
most citedleast cited
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