Massachusetts Institute of Technology · EngineeringChung Connectomics Lab
Kwanghun Chung · Cambridge, Massachusetts
Research Focus
Dr. Kwanghun Chung's lab at MIT focuses on understanding Alzheimer's disease by studying the locus coeruleus, a brain region that is affected early in the disease. They analyze how this area connects with other parts of the brain and how those connections change with age and disease progression. By examining neuron populations and their properties, the lab aims to uncover the reasons behind the vulnerability of certain brain regions to Alzheimer's.
Alzheimer's Diseasebrain mappinglocus coeruleusconnectomicsaging
Research Aims
5AIM 01Investigate the connectivity of the locus coeruleus with other brain regions.
AIM 02Characterize neuron populations in the locus coeruleus affected by aging and Alzheimer’s disease.
AIM 03Examine input/output relationships in neurons of the entorhinal cortex.
AIM 04Develop high-resolution maps of brain connectivity relating to Alzheimer's pathology.
AIM 05Utilize experimental models to understand disease progression in Alzheimer’s.
Skills the Lab Values
3-Dimensional imagingsingle-cell analysismicroscopymouse modelsmolecular profiling
Output against the department
Publications118bottom 26% of dept.206th of 278
this lab
most publishedleast published
Citations11ktop 35% of dept.96th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.