Columbia University in the City of New York · GeneticsMorphogen Signaling and Development Lab
Gary Struhl · New York, New York
Research Focus
Gary Struhl's lab at Columbia University focuses on understanding how signaling molecules, known as morphogens, control the growth and patterning of organs during development using the fruit fly Drosophila as a model organism. The research explores the complex interactions between these morphogens, their receptors, and the genetic elements they regulate, aiming to uncover insights that could inform therapeutic strategies for various human diseases, particularly developmental disorders and cancers.
morphogensDrosophilaorgan growthgene expressionsignal transductiondevelopmental biologycancer researchsignaling pathwaysBMPsWnts
Research Aims
3AIM 01Investigate how morphogens control organ growth in Drosophila.
AIM 02Determine the roles of BMPs and Wnts in gene expression and growth regulation.
AIM 03Identify genetic mechanisms that integrate signaling for organ development.
Skills the Lab Values
gene editingtransgenic organism techniquesmolecular cloningPCRcell cultureconfocal microscopygenetic analysisbioinformaticscell signaling assaysin situ hybridization
Output against the department
Publications109bottom 33% of dept.173rd of 259
this lab
most publishedleast published
Citations22ktop 26% of dept.68th of 259
this lab
most citedleast cited
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