University of Illinois Urbana-Champaign · Microbiology & ImmunologyBrooke Immunology Lab
Christopher Byron Brooke · Champaign, Illinois
Research Focus
Dr. Christopher Byron Brooke's lab at the University of Illinois focuses on understanding how the immune system responds to influenza viruses. By studying how the virus interacts with the immune system during natural infections, the lab aims to identify key factors that influence how effectively vaccines can prevent severe infections and transmission. Their work combines clinical research with computational modeling to improve future vaccine development and public health strategies.
influenza virusimmune responsevaccinesviral sheddingB cell repertoire
Research Aims
5AIM 01Investigate the immune response dynamics during influenza virus infection.
AIM 02Identify immune correlates of reduced viral transmission risk.
AIM 03Understand how vaccination influences immune memory evolution.
AIM 04Develop computational models to predict vaccine effectiveness.
AIM 05Explore host and viral factors that shape antibody responses.
Skills the Lab Values
PCRblood samplingimmunological assaysmachine learningstatistical modelingdata analysisclinical research methodslongitudinal studiesvirus culturehigh-dimensional data analysis
Output against the department
Publications108bottom 39% of dept.293rd of 486
this lab
most publishedleast published
Citations3.0kbottom 21% of dept.384th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.