University of Colorado Boulder · BiologyAdvanced Imaging for Structural Biology Lab
Michael H. B. Stowell · Boulder, Colorado
Research Focus
Dr. Michael Stowell's lab at the University of Colorado focuses on developing advanced imaging technologies to better understand the dynamic structures of biological molecules. They create systems that improve cryogenic electron microscopy, allowing scientists to capture the changing nature of proteins and other complex biological systems over time. This research aims to shed light on how these structures influence health and disease, paving the way for new therapies.
cryogenic electron microscopytime-resolved imagingmacromolecular complexesstructural biologybiophysics
Research Aims
5AIM 01Develop a patterned illumination system for cryoTREM.
AIM 02Capture multiple temporal states of biological systems.
AIM 03Integrate data processing methods to analyze time-resolved structures.
AIM 04Investigate structural dynamics of proteins related to disease.
AIM 05Create tools to advance the field of cryogenic sample analysis.
Skills the Lab Values
cryo-electron microscopysample preparationdevice designdata processingoptical imagingfluorescence microscopy
Output against the department
Publications105bottom 36% of dept.653rd of 1,033
this lab
most publishedleast published
Citations5.0kbottom 38% of dept.643rd of 1,033
this lab
most citedleast cited
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