Johns Hopkins University · BiologyMeeker Lab
Alan Keith Meeker · Baltimore, Maryland
Research Focus
Dr. Alan Keith Meeker's lab at Johns Hopkins University focuses on understanding prostate cancer treatment responses by investigating a telomere biomarker. This research aims to determine which patients might benefit from additional therapies after prostate surgery, helping to personalize and improve treatment decisions. By using advanced analysis of tumor biology, the lab seeks to identify patients who would either not benefit from aggressive treatments or who may need them to prevent disease progression.
prostate cancersalvage therapytelomere biomarkerradiation therapyanti-androgen therapy
Research Aims
3AIM 01Evaluate the telomere biomarker's predictive power for treatment response in prostate cancer post-surgery.
AIM 02Determine if aggressive salvage therapy improves outcomes for men based on telomere biomarker categories.
AIM 03Assess progression rates of prostate cancer in patients treated with different therapeutic approaches.
Skills the Lab Values
tissue microarray analysisimmunohistochemistryquantitative image analysisCox regression modelingbiomarker discoverypatient stratificationclinical trial evaluation
Output against the department
Publications419top 11% of dept.110th of 1,033
this lab
most publishedleast published
Citations21ktop 18% of dept.186th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.