University of Pennsylvania · Biomedical EngineeringThe FLASH Therapy Lab
Constantinos Koumenis · Philadelphia, Pennsylvania
Research Focus
Dr. Constantinos Koumenis' lab at the University of Pennsylvania focuses on improving radiation therapy for cancer patients. They are studying a new technique called FLASH radiotherapy, which uses a high dose of radiation to minimize damage to healthy tissues while effectively targeting tumors. Their research aims to understand how this innovative approach can protect normal tissues during treatments for various cancers, including pancreatic and lung cancer.
FLASH radiotherapycancer treatmentparticle therapypancreatic cancerlung cancernormal tissue sparingradiation toxicitypreclinical studiespencil beam scanning
Research Aims
4AIM 01Investigate the dosimetric and biophysical properties of FLASH proton therapy in pancreatic cancer.
AIM 02Explore FLASH radiotherapy's potential to reduce treatment-related injuries in sarcomas.
AIM 03Compare the effectiveness of FLASH radiotherapy with carbon ions against traditional methods.
AIM 04Develop technological advancements in pencil beam scanning for FLASH radiotherapy.
Skills the Lab Values
radiation therapy techniquesmouse modelsdose delivery algorithmsp53 genetic studiesCANINE osteosarcoma trialsbiostatisticsdosimetrytissue immunofluorescencefunctional imaging
Output against the department
Publications485top 17% of dept.99th of 595
this lab
most publishedleast published
Citations20ktop 16% of dept.98th of 595
this lab
most citedleast cited
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