University of Washington-Seattle Campus · Biomedical EngineeringVascular Health and Calcification Lab
Cecilia M Giachelli · Seattle, Washington
Research Focus
Dr. Cecilia Giachelli's lab at the University of Washington is focused on understanding how and why calcium builds up in blood vessels and heart valves, a process known as vascular calcification. This condition can lead to serious heart issues, especially in older adults and those with diabetes or kidney disease. The lab investigates the biological processes and genetic factors involved in this calcification to identify potential treatments and biomarkers that can improve cardiovascular health and prevent complications.
vascular calcificationcardiovascular diseasediabeteskidney diseasebiomarker identificationtherapeutic targetscell culturegenetic pathwaysorgan models
Research Aims
5AIM 01Investigate the genetic pathways that regulate vascular calcification.
AIM 02Identify key risk factors for vascular calcification related to chronic diseases.
AIM 03Develop biomarkers for early detection of vascular calcification.
AIM 04Evaluate potential therapeutic targets for preventing vascular calcification.
AIM 05Understand the biological mechanisms underlying calcification in cardiovascular health.
Skills the Lab Values
cell culture techniquesanimal modelsorganoid studiesgenetic analysisbiomarker identificationsignal pathway mappinghemodynamic assessmentsclinical research methodologiestranslational research
Output against the department
Publications239top 43% of dept.253rd of 595
this lab
most publishedleast published
Citations31ktop 8% of dept.50th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.