University of Alabama at Birmingham · Biomedical EngineeringWang Cardiovascular Lab
Yajing Wang · Birmingham, Alabama
Research Focus
Dr. Yajing Wang's research lab at the University of Alabama at Birmingham focuses on improving treatments for patients suffering from diabetic ischemic heart failure. By studying the role of specific cardiac proteins and cell therapies, the lab aims to engineer small extracellular vesicles that enhance heart protection in diabetic conditions. Their goal is to restore the heart's function by modifying the local microenvironment with advanced biomaterials.
ishemic heart failurediabetesextracellular vesiclescell therapybiomedical engineeringcardiovascular diseasecardiokinesN-cadherinadipose tissuetherapeutic interventions
Research Aims
3AIM 01Investigate how bioengineered small extracellular vesicles can protect the heart against ischemic injury in diabetic conditions.
AIM 02Determine the role of the cardiokine CTRP9 in influencing small extracellular vesicle production from adipose-derived stromal cells.
AIM 03Explore the mechanisms by which surface proteins on small extracellular vesicles contribute to their cardioprotective effects.
Skills the Lab Values
cell culturegenetic engineeringsmall extracellular vesicles isolationcardiac assaysanimal modelsproteomicsdata analysismicroscopybiomaterials fabricationWestern blotting
Output against the department
Publications1,212top 4% of dept.21st of 595
this lab
most publishedleast published
Citations15ktop 24% of dept.141st of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.