University of Arizona · BiologyCentriole Dynamics Lab
Gregory Charles Rogers · Tucson, Arizona
Research Focus
Dr. Gregory Charles Rogers' research lab at the University of Arizona focuses on understanding the structure and function of centrosomes, which are essential organelles in cells that organize microtubules. The lab investigates how centrioles, the core components of centrosomes, duplicate and elongate, and how this process is regulated. This work is crucial as misregulated centriole duplication can lead to serious health issues such as birth defects and cancer.
centriole duplicationcentrosomemicrotubulescell cycleciliopathycancerDrosophilaprotein complexPLK4autophosphorylation
Research Aims
5AIM 01Identify the molecular mechanisms that suppress centrosome amplification
AIM 02Characterize how mother centrioles select a site for daughter centriole assembly
AIM 03Determine the composition and formation of pre-procentrioles
AIM 04Investigate how Plk4 promotes the assembly of nascent daughter centrioles
AIM 05Understand the regulatory mechanisms controlling centriole length.
Skills the Lab Values
cell cultureDrosophila geneticsprotein purificationimmunostainingmicroscopyWestern blotRNA sequencingphosphorylation assaysflow cytometrydata analysis
Output against the department
Publications1bottom 1% of dept.1,029th of 1,033
this lab
most publishedleast published
Citations2bottom 1% of dept.1,025th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.