Washington University in St Louis · NeuroscienceMorris Biomarkers Lab
John Morris · Saint Louis, Missouri
Research Focus
Dr. John Morris's lab at Washington University focuses on understanding Alzheimer's disease by investigating early biomarkers in middle-aged individuals, especially those with a family history of the disease. The lab studies how changes in the brain can indicate the potential onset of Alzheimer's, even before symptoms appear. Through various projects, they explore factors that may influence the progression from preclinical conditions to symptomatic Alzheimer's while examining biological tests and lifestyle factors that may impact brain health.
Alzheimer's Diseasebiomarkerscognitive healthpreclinical Alzheimer'stauopathy
Research Aims
4AIM 01Identify molecular markers for Alzheimer's disease in cognitively normal individuals.
AIM 02Characterize the course of preclinical Alzheimer's disease progression.
AIM 03Examine the role of tau burden in preclinical Alzheimer's disease.
AIM 04Investigate how lifestyle factors like physical activity affect Alzheimer's progression.
Skills the Lab Values
magnetic resonance imaging (MRI)plasma biomarker analysiscerebrospinal fluid analysislongitudinal cohort study designstatistical data management
Output against the department
Publications2,367top 1% of dept.3rd of 671
this lab
most publishedleast published
Citations236ktop 1% of dept.1st of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.