University of California-Irvine · ChemistryNanostructured Biosensing Unit
Eric Olaf Potma · Irvine, California
Research Focus
The lab of Eric Olaf Potma at UC Irvine focuses on developing advanced biosensing techniques that allow for the rapid detection of individual molecules without the need for labels. By combining innovative optical methods with engineered nanostructures, the research aims to enhance the speed and specificity of molecular identification, particularly in DNA analysis. This work has the potential to revolutionize fields such as genomics and diagnostics by enabling quicker and more accurate assessments of genetic material.
biosensingultrahigh speedRaman scatteringnanophotonicssingle molecule detectionDNA sequencingepigeneticsnanostructures
Research Aims
5AIM 01Develop novel biosensing techniques for rapid detection of single molecules
AIM 02Enhance acquisition speed of Raman-based biosensing by over four orders of magnitude
AIM 03Combine coherent Raman scattering with dielectric nanophotonic designs
AIM 04Create thermally robust platforms for label-free molecular detection
AIM 05Enable new applications in DNA analysis and epigenetic modification detection.
Skills the Lab Values
surface-enhanced Raman scatteringcoherent anti-Stokes Raman scatteringnanostructure designmicroscopymicrofluidicssignal acquisitionoptical engineeringspectroscopyexperimental design
Output against the department
Publications336top 33% of dept.70th of 216
this lab
most publishedleast published
Citations10ktop 47% of dept.101st of 216
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.