University of Florida · PhysiologyEnvironmental Toxicogenomics Lab
Christopher D Vulpe · Gainesville, Florida
Research Focus
Dr. Christopher D. Vulpe's lab at the University of Florida focuses on how genetic differences influence people's responses to toxic substances. Using innovative CRISPR technology, the lab investigates which specific genes make individuals more or less resilient to environmental toxins. The research aims to enhance our understanding of genetic and environmental interactions, which is crucial for predicting health risks and improving public safety.
CRISPRgenetic variationenvironmental toxinstoxicogenomicspublic health
Research Aims
5AIM 01Identify common genetic variants that impact resilience to toxicants.
AIM 02Evaluate the functional role of specific genes in response to environmental toxins.
AIM 03Develop methods to improve risk assessment of toxic exposures in diverse populations.
AIM 04Investigate gene-by-environment interactions linked to public health outcomes.
AIM 05Utilize advanced cell models for testing gene function related to toxicant exposure.
Skills the Lab Values
CRISPR screeningsingle-cell RNA sequencingcell culture techniquesgene expression analysistoxicology modeling
Output against the department
Publications265top 21% of dept.59th of 286
this lab
most publishedleast published
Citations15ktop 21% of dept.60th of 286
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.