Baylor College of Medicine · GeneticsAlzheimer's Genetic Research Lab
Olivier Lichtarge · Houston, Texas
Research Focus
Dr. Olivier Lichtarge's lab at Baylor College of Medicine focuses on understanding Alzheimer's Disease by exploring genetic factors and how they differ between men and women. The lab uses advanced computational methods to analyze genetic data, aiming to identify key genes that contribute to the risk of Alzheimer's. Through experimental validation in model organisms, the lab works to improve and tailor strategies for early detection and treatment of Alzheimer's Disease based on genetic insights.
Alzheimer's Diseasegenetic risk factorsgender differencesmachine learninggenomicscomputational biologybiomarkersDrosophila modelsevolutionary analysis
Research Aims
3AIM 01Identify genes associated with Alzheimer's Disease risk in men and women separately.
AIM 02Develop machine learning frameworks to analyze genetic data related to Alzheimer's Disease.
AIM 03Validate potential Alzheimer's biomarkers through experiments in Drosophila and mammalian models.
Skills the Lab Values
machine learninggenome-wide association studies (GWAS)Drosophila genetic modelshuman genetic variant analysismolecular biology techniqueshigh-throughput screeningexperimental validationstatistical data analysisbioinformatics
Output against the department
Publications368top 21% of dept.53rd of 259
this lab
most publishedleast published
Citations18ktop 31% of dept.80th of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.