University of Alabama at Birmingham · Biomedical EngineeringCancer Imaging Initiative
Bernadette Marquez-Nostra · Birmingham, Alabama
Research Focus
Dr. Bernadette Marquez-Nostra's lab focuses on improving cancer treatment response for patients with aggressive forms of breast and lung cancer. By developing advanced imaging techniques, the lab aims to better understand how new bispecific antibodies work to target cancer cells. This research hopes to make it easier for doctors to identify which patients will benefit most from these therapies, potentially transforming treatment approaches for cancer.
cancer therapybispecific antibodiesimaging techniquestumor responselung cancerbreast cancerPET imagingprecision medicinecompanion diagnostics
Research Aims
5AIM 01Develop PET imaging biomarkers to evaluate drug delivery to tumors
AIM 02Assess changes in receptor status in vivo in response to antibody therapy
AIM 03Produce a toolkit for monitoring treatment response in cancer patients
AIM 04Investigate the mechanisms of action for bispecific antibodies
AIM 05Establish companion diagnostics to enhance patient selection for new therapies.
Skills the Lab Values
PET imagingantibody therapypreclinical modelsanimal modelingimmunohistochemistrydata analysisflow cytometrycell culturemolecular biology techniques
Output against the department
Publications54bottom 7% of dept.556th of 595
this lab
most publishedleast published
Citations843bottom 5% of dept.567th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.