University of California-Berkeley · NeuroscienceFeldman Inhibition Lab
Daniel Feldman · Berkeley, California
Research Focus
Dr. Daniel Feldman's research lab at UC Berkeley focuses on understanding how certain brain cells, called inhibitory interneurons, regulate their activity in response to sensory experiences and learning. The lab investigates how these changes may play a role in conditions like autism, particularly looking at molecular mechanisms and plasticity in different types of interneurons. By studying how these cells can adapt in the somatosensory cortex, the research aims to uncover new therapeutic targets for improving brain function in autism and similar disorders.
inhibitory interneuronsintrinsic plasticityautismsomatosensory cortexmolecular mechanisms
Research Aims
3AIM 01Identify the molecular pathways mediating intrinsic plasticity in inhibitory interneurons.
AIM 02Test the hypothesis that deficits in intrinsic plasticity are involved in autism-related circuit dysfunction.
AIM 03Characterize plasticity in somatostatin circuits to explore similarities with parvalbumin circuits.
Skills the Lab Values
immunohistochemistryRNA sequencingmouse modelspharmacological techniquesgene expression analysis
Output against the department
Publications221top 33% of dept.223rd of 671
this lab
most publishedleast published
Citations35ktop 10% of dept.69th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.