Ohio State University-Main Campus · Microbiology & ImmunologyThe Immune Dynamics Lab
Amal O Amer · Columbus, Ohio
Research Focus
Dr. Amal O. Amer's research lab focuses on understanding the immune response and disease mechanisms related to viral infections and neurodegenerative diseases. The lab's major projects examine the role of specific immune pathways in COVID-19 and Alzheimer's disease, as well as how immune cells respond to infections like Legionella. By investigating the underlying biological processes, the lab aims to identify new therapeutic targets for treating these complex diseases.
SARS-CoV-2COVID-19Alzheimer's diseaseinflammasomemicroRNAimmune responseneuroinflammationLegionella pneumophilaautophagy
Research Aims
5AIM 01Investigate the mechanisms of SARS-CoV-2-mediated pathology and coagulopathy.
AIM 02Examine how specific microRNA levels affect autophagy in Alzheimer's disease.
AIM 03Determine the role of non-canonical inflammasomes in innate immunity against Legionella.
AIM 04Identify novel therapeutic targets for COVID-19 and Alzheimer's disease.
AIM 05Understand the immune response pathways involved in multi-organ damage during infections.
Skills the Lab Values
PCRcell cultureanimal modelsRNA sequencingmicroscopyproteomicsbioinformaticshigh-resolution imaginggene editingflow cytometry
Output against the department
Publications145top 45% of dept.219th of 486
this lab
most publishedleast published
Citations21ktop 18% of dept.88th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.