Cornell University · EngineeringLipid Nanoparticle Immunology Lab
Shaoyi Jiang · Ithaca, New York
Research Focus
Dr. Shaoyi Jiang's lab at Cornell University focuses on understanding how lipid nanoparticles (LNPs) interact with the immune system. By studying the immunogenicity of these nanoparticles, the lab aims to identify which components of LNPs cause adverse immune responses, particularly in the context of vaccine development. Their research seeks to improve the safety and effectiveness of LNPs used in vaccines and therapeutics.
lipid nanoparticlesimmunogenicityCOVID-19 vaccinevaccine developmentimmune response
Research Aims
5AIM 01Investigate the immunogenicity of lipid nanoparticles used in vaccines.
AIM 02Identify key lipid components that induce immune responses.
AIM 03Assess local and systemic inflammatory effects of LNP injections.
AIM 04Analyze the relationship between LNP chemical properties and immune activation.
AIM 05Develop low-immunogenicity lipid nanoparticle formulations for clinical use.
Skills the Lab Values
immunological assayscell culturecytokine profilinggene expression analysisanimal modelsin vitro experimentslipid formulationdata analysis with Pythonflow cytometry
Output against the department
Publications291top 29% of dept.82nd of 278
this lab
most publishedleast published
Citations33ktop 8% of dept.23rd of 278
this lab
most citedleast cited
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