Duke University · Biomedical EngineeringThe Astrocyte Recovery Lab
Tatiana Segura · Durham, North Carolina
Research Focus
Dr. Tatiana Segura's lab at Duke University focuses on developing innovative biomaterials to aid recovery after ischemic stroke. By utilizing extracellular vesicles from activated astrocytes, the lab explores new therapies that promote brain repair and regeneration instead of merely protecting against damage. The ultimate goal is to create effective treatments that target the underlying issues of stroke-related disabilities, offering new hope for patients.
biomaterialsischemic strokebrain regenerationextracellular vesiclesastrocytestherapeutic interventionsneuroengineeringfunctional recovery
Research Aims
4AIM 01Develop bioengineered therapies that promote recovery after stroke.
AIM 02Study the effects of reactive astrocyte-derived extracellular vesicles in brain repair.
AIM 03Investigate different delivery methods for vesicle-based therapies.
AIM 04Characterize human-derived astrocyte extracellular vesicles for clinical application.
Skills the Lab Values
tissue engineeringbiomaterials characterizationcell culture techniquesanimal modelsmicroscopybiochemical assayshydrogel synthesisintracranial injections
Output against the department
Publications185bottom 43% of dept.338th of 595
this lab
most publishedleast published
Citations13ktop 26% of dept.156th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.