Icahn School of Medicine at Mount Sinai · Microbiology & ImmunologyVaccine Immunology and B Cell Dynamics Lab
Goran Bajic · New York, New York
Research Focus
Dr. Goran Bajic's research lab focuses on understanding how our immune system responds to vaccines and infections, especially in the context of evolving viruses like SARS-CoV-2. The lab utilizes advanced techniques to study B cells, which play a crucial role in producing antibodies. By analyzing how these immune responses develop at a molecular level, the lab aims to improve vaccine design and enhance our capacity to fight rapidly changing pathogens, including various coronaviruses.
B cell responsesvaccine developmentSARS-CoV-2structural biologyimmune memoryantibody affinity maturationantigenic variationimmunodominanceviral evolution
Research Aims
3AIM 01Define immunodominance in biochemical and structural terms using human B cells.
AIM 02Investigate how pre-existing immunity affects memory B cell responses to vaccines.
AIM 03Map the structural features of antibody responses to evolving viral pathogens.
Skills the Lab Values
Cryo-electron microscopyB cell culture techniquesGenetic sequencingAntibody specificity assaysImmunological mappingFlow cytometryMolecular cloningData analysis using PythonStructural biology methods
Output against the department
Publications86bottom 28% of dept.346th of 486
this lab
most publishedleast published
Citations3.6kbottom 27% of dept.357th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.