UTHThe University of Texas Health Science Center at Houston · Neuroscience
The NeuroVigilance Lab
Fudong Liu · Houston, Texas
Research Focus
Dr. Fudong Liu's lab focuses on understanding the intricate mechanisms behind stroke and neuroinflammation, particularly how gender differences and aging influence these processes. They investigate how factors like the X chromosome and hormonal changes after menopause affect stroke outcomes in women. Additionally, the lab explores the role of immune signaling pathways, specifically CD200-CD200R interactions, in modulating neuroinflammation and improving recovery from stroke.
strokeneuroinflammationX chromosomeCD200 signalinghormonal effectsagingimmune responsemenopauseneuroprotection
Research Aims
5AIM 01Investigate the role of Kdm6a gene escape from XCI in aging-related stroke outcomes in women.
AIM 02Examine the effects of early and late estrogen replacement therapy on post-stroke inflammation.
AIM 03Evaluate how CD200-CD200R signaling influences immune cell activation during stroke.
AIM 04Analyze the interaction between endothelial CD200 signaling and peripheral immune cell migration after stroke.
AIM 05Determine the impact of neuronal CD200 signaling on inflammation and recovery outcomes post-stroke.
Skills the Lab Values
mouse modelsin vitro assaysconditional knockout techniquesgene expression analysisimmunohistochemistryflow cytometrycell cultureWestern blottingRNA sequencing
Output against the department
Publications275top 26% of dept.172nd of 671
this lab
most publishedleast published
Citations14ktop 29% of dept.197th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.