University of Toledo · ChemistryTaylor Lab
William R. Taylor · Toledo, Ohio
Research Focus
Dr. William R. Taylor's research lab at the University of Toledo focuses on understanding the mechanisms that regulate cell division (mitosis) and a specific form of cell death known as ferroptosis. By creating and studying novel small molecules, his team aims to improve cancer treatments by targeting both processes simultaneously. Their work explores how these cellular pathways intersect and how this knowledge can be used to develop better anti-cancer therapies.
mitosisferroptosissmall moleculescell divisioncancer therapy
Research Aims
3AIM 01Investigate how imidazole-based chalcones affect tubulin and induce mitotic arrest.
AIM 02Explore the relationship between prolonged mitotic arrest and sensitivity to ferroptosis.
AIM 03Use a lentiviral system to identify genetic regulators that link mitosis and ferroptosis.
Skills the Lab Values
cell culturelive-cell microscopyRNA sequencinggenetic screeningmolecular hybridizationdrug designbiochemical assaysconfocal microscopy
Output against the department
Publications193bottom 46% of dept.117th of 216
this lab
most publishedleast published
Citations18ktop 27% of dept.58th of 216
this lab
most citedleast cited
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