University of Connecticut · NeuroscienceThe Corneal Injury Initiative
Royce Mohan · Storrs, Connecticut
Research Focus
The research lab of Dr. Royce Mohan at the University of Connecticut focuses on understanding injuries to the cornea caused by chemical agents like sulfur mustard. They investigate the molecular changes that occur in response to these injuries, particularly how specific proteins are modified and how sensory nerve cells in the cornea are affected. This research aims to identify new biological markers and targets for improving recovery from such damage.
corneal injurysulfur mustardcitrullinationsensory dysfunctionSchwann cellsaxonal regenerationtranscriptomicsproteomicsbiomarkerschemical injury
Research Aims
5AIM 01Investigate proteins altered by PAD4-driven citrullination in corneal tissues.
AIM 02Validate and assess the function of citrullinated proteins in epithelial cell cultures.
AIM 03Identify druggable targets in corneal Schwann cells for promoting regeneration.
AIM 04Examine transcriptomic changes in injured corneas to find new regenerative effectors.
AIM 05Establish biomarkers for corneal injury and repair mechanisms.
Skills the Lab Values
cell culture techniquesRNA sequencingproteomicsimmunohistochemistrybioinformaticstransgenic modelsgene knockoutmass spectrometryprotein analysisfunctional assays
Output against the department
Publications125bottom 44% of dept.372nd of 671
this lab
most publishedleast published
Citations4.5kbottom 33% of dept.450th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.