University of Pittsburgh-Pittsburgh Campus · Microbiology & ImmunologyEpstein-Barr Virus Research Unit
Renfeng Li · Pittsburgh, Pennsylvania
Research Focus
Dr. Renfeng Li's lab at the University of Pittsburgh focuses on understanding the Epstein-Barr virus (EBV), a virus linked to various cancers. The lab studies how the ASB13 protein influences the life cycle of EBV, particularly how it regulates viral replication and reactivation in B cells. Their research aims to uncover new therapeutic strategies for treating EBV-related diseases by targeting the virus's behavior in human cells.
EBVcancerASB13viral reactivationB-cell lymphoma
Research Aims
3AIM 01Determine how ASB13 inhibits SYK signaling to restrict EBV replication in B cells.
AIM 02Investigate ASB13's impact on EBV RTA stability and viral protein regulation.
AIM 03Explore how ASB13 is degraded to facilitate EBV lytic replication.
Skills the Lab Values
CRISPR/Cas9cell cultureimmunoprecipitationWestern blotRNA sequencing
Output against the department
Publications390top 9% of dept.44th of 486
this lab
most publishedleast published
Citations7.1ktop 50% of dept.244th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.