Georgia Institute of Technology-Main Campus · ChemistryProstate Cancer Therapeutics Lab
Adegboyega Oyelere · Atlanta, Georgia
Research Focus
Dr. Adegboyega Oyelere's lab at Georgia Tech focuses on developing new treatments for prostate cancer, particularly advanced cases known as castration-resistant prostate cancer (CRPC). The team is working on small molecules that can target the androgen receptor, which is crucial for the growth of prostate cancer cells, and the biological processes that affect how these receptors function. By creating treatment agents that can effectively inhibit cancer growth through multiple mechanisms, the lab aims to overcome current limitations of prostate cancer therapies.
prostate cancerandrogen receptorepigeneticsHDAC inhibitorssmall moleculesdrug developmentantiandrogenscancer therapyxenograft models
Research Aims
3AIM 01Develop small molecules that target androgen receptors and HDAC for prostate cancer treatment.
AIM 02Investigate the mechanisms of action of novel antiandrogen-HDAC inhibitors.
AIM 03Evaluate the effectiveness of new compounds on castration-resistant prostate cancer models.
Skills the Lab Values
drug synthesiscell culture techniquesin vitro testinganimal modelingpharmacokineticshistorical analysis of drug effectsbiochemical assaysmolecular cloninghistone modification analysis
Output against the department
Publications134bottom 32% of dept.146th of 216
this lab
most publishedleast published
Citations4.2kbottom 31% of dept.150th of 216
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.