University of South Florida · PhysiologyVascular Barrier Research Lab
Sarah Y Yuan · Tampa, Florida
Research Focus
Dr. Sarah Y Yuan's lab focuses on understanding how vascular barriers function during inflammation and injury, which can lead to various cardiovascular diseases. The lab investigates the mechanisms behind vascular permeability, especially how certain blood components leak into surrounding tissues during diseases like sepsis and stroke. They aim to discover new diagnostic and therapeutic targets to help develop effective treatments for these conditions.
vascular permeabilityinflammationendothelial cellsvascular barriercardiovascular diseases
Research Aims
3AIM 01Identify key factors that cause vascular barrier leakage.
AIM 02Characterize endothelial surface receptors involved in permeability.
AIM 03Investigate molecular events at cell-cell junctions during inflammation.
Skills the Lab Values
molecular biology techniquesmicrovascular imaginganimal modelscell culturesignal transduction analysis
Output against the department
Publications174top 40% of dept.112th of 286
this lab
most publishedleast published
Citations5.7kbottom 46% of dept.155th of 286
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.