Northwestern University · BiologyErythropoiesis Research Lab
Peng Ji · Evanston, Illinois
Research Focus
Dr. Peng Ji's lab at Northwestern University focuses on understanding the development of red blood cells and the impact of inflammation on blood disorders. They compare the unique environments that support red blood cell development in mice and humans, aiming to uncover critical differences that could lead to new treatments for diseases like myelodysplastic syndromes (MDS). The research uses advanced techniques to study how immune responses affect blood cell production and maturation, which is vital for addressing health issues associated with aging and chronic inflammation.
erythropoiesismyelodysplastic syndromesinflammationgasdermin Derythroblastic islandsmacrophagesstem cell biologyimmunotherapy
Research Aims
3AIM 01Investigate the structure and function of erythroblastic islands in mice and humans.
AIM 02Understand the role of gasdermin D in the development and progression of myelodysplastic syndromes.
AIM 03Explore the inflammatory mechanisms affecting hematopoiesis in bone marrow during disease conditions.
Skills the Lab Values
spatial transcriptomicsmouse modelsinduced pluripotent stem cells (iPSC)immunofluorescencecell culturesingle-cell RNA sequencingflow cytometrygene editing (CRISPR)
Output against the department
Publications208top 31% of dept.323rd of 1,033
this lab
most publishedleast published
Citations3.7kbottom 28% of dept.739th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.