University of California-Davis · BiologyHong Lab
Hong Ji · Davis, California
Research Focus
Dr. Hong Ji's lab at UC Davis focuses on understanding how air pollution affects lung health, particularly through the study of specific molecular mechanisms in airway cells. The team's research investigates how TET1, a protein involved in modifying DNA, interacts with RNA modifications that impact inflammation caused by particulate matter. Their work aims to uncover the details of these interactions to help find new ways to treat lung diseases triggered by pollution.
air pollutionlung inflammationepigeneticsm6A RNA modificationTET1particulate matteroxidative stress
Research Aims
3AIM 01Investigate how TET1 regulates m6A reader enzymes in airway epithelial cells.
AIM 02Identify changes in RNA m6A levels following exposure to particulate matter and TET1 loss.
AIM 03Examine the interactions between TET1 and m6A readers at specific genomic locations.
Skills the Lab Values
gene expression analysischromatin accessibility assaysRT-qPCRRNA sequencingimmunoprecipitation techniquesdata analysis using Rbioinformaticsmouse modelscell culture
Output against the department
Publications190top 34% of dept.348th of 1,033
this lab
most publishedleast published
Citations1.1kbottom 5% of dept.978th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.