University of California-Berkeley · BiochemistryOhainle Virology Lab
Molly Ohainle · Berkeley, California
Research Focus
Molly Ohainle's lab focuses on understanding how human cells defend against HIV and related viruses from primates. They investigate the molecular mechanisms by which certain host genes can restrict the infection of these viruses. The research aims to identify and manipulate host factors that limit HIV replication, which could lead to new treatments or even a cure for HIV infection.
HIVlentivirusviral infectionCRISPRhost immunitycross-species transmissiongenetic screeningviral resistancechromatin modificationsantiviral genes
Research Aims
3AIM 01Identify the mechanisms by which human cells restrict primate lentiviral infections.
AIM 02Define how different lentiviral capsids are inhibited in human cells.
AIM 03Explore host resistance mechanisms against a variety of HIV and SIV strains.
Skills the Lab Values
CRISPR screeningcell culturemolecular cloninggenetic screeningRNA extractionWestern blotmicroscopyPCRchromatin immunoprecipitationbioinformatics
Output against the department
Publications30bottom 2% of dept.395th of 402
this lab
most publishedleast published
Citations1.1kbottom 3% of dept.388th of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.