Indiana University-Purdue University-Indianapolis · BiologyVidal Lab
Ruben Vidal · Indianapolis, Indiana
Research Focus
Dr. Ruben Vidal's lab investigates brain disorders related to tau proteins, particularly tauopathies, which are associated with neurodegeneration. Using advanced imaging techniques, the team studies the structures of tau aggregates and how they influence diseases like progressive supranuclear palsy and new forms of tauopathies. Their research aims to improve understanding of these conditions, which can lead to better diagnoses and treatments.
tauopathiesneurodegenerationprogressive supranuclear palsytau structurein vivo models
Research Aims
3AIM 01Characterize the prevalence and neuropathologic features of novel 4R tauopathies in large cohorts of patients.
AIM 02Identify molecular changes in tau proteins specific to novel tauopathies.
AIM 03Characterize tau propagation using custom microfluidic devices and murine models.
Skills the Lab Values
cryo-electron microscopymouse modelsbiochemical analysismolecular characterizationstructural biology
Output against the department
Publications217top 29% of dept.299th of 1,033
this lab
most publishedleast published
Citations12ktop 31% of dept.324th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.