University of Illinois Chicago · PhysiologyFructose Metabolism Lab
Chong Wee Liew · Chicago, Illinois
Research Focus
Dr. Chong Wee Liew's research focuses on how the body processes fructose, particularly in brown adipose tissue, which is important for energy regulation and metabolism. His lab is investigating how a high-fructose diet affects the functioning and health of brown fat, and the implications this has for obesity and diseases like type 2 diabetes. By studying the role of specific transporters and gut microbiota, they aim to uncover the mechanisms behind fructose-induced metabolic changes.
fructose metabolismbrown adipose tissueobesitygut microbiometype 2 diabetes
Research Aims
5AIM 01Investigate the impact of Glut5 on fructose metabolism in brown adipose tissue.
AIM 02Determine the effects of a high-fructose diet on iBAT metabolic function.
AIM 03Explore how gut microbiota influences Glut5 expression in response to diet.
AIM 04Analyze the relationship between fructose intake and metabolic diseases.
AIM 05Assess the role of liver X receptors in brown adipocyte function.
Skills the Lab Values
cell culturegene expression analysisanimal modelsRNA sequencingWestern blottranscriptomic analysismicrobiota assessmentlipid profiling
Output against the department
Publications91bottom 23% of dept.219th of 286
this lab
most publishedleast published
Citations4.9kbottom 42% of dept.166th of 286
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.