New York University · NeuroscienceSpinal Cord Development and Motor Circuit Lab
Jeremy S Dasen · New York, New York
Research Focus
Dr. Jeremy S. Dasen's lab at New York University School of Medicine studies how neurons in the spinal cord assemble the networks necessary for controlling movement. They focus on understanding the genetic factors that shape these neurons during development, particularly the role of Hox transcription factors in creating different types of motor neurons. The lab aims to uncover the molecular mechanisms behind motor circuit formation, which could lead to therapies for spinal cord injuries and diseases.
Hox proteinsmotor neuronsspinal cordneural circuitsgenesdevelopmentsynaptic specificitymotor behaviorrehabilitationneurogenetics
Research Aims
5AIM 01Investigate the role of Hox transcription factors in motor neuron development.
AIM 02Elucidate mechanisms of synaptic specificity in spinal circuits.
AIM 03Determine how genetic programs influence motor circuit assembly.
AIM 04Analyze the relationship between neuronal diversification and motor behaviors.
AIM 05Explore therapeutic strategies for injuries affecting spinal circuits.
Skills the Lab Values
genetic manipulationspinal cord dissectioncell cultureimaging techniquesbehavioral assaystranscription factor analysisgenomic analysiscomparative vertebrate studiescircuit tracing techniquesmolecular cloning
Output against the department
Publications75bottom 21% of dept.529th of 671
this lab
most publishedleast published
Citations7.5ktop 49% of dept.331st of 671
this lab
most citedleast cited
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