University of California-Davis · PharmacologyAtrial Fibrillation Gender Research Lab
Eleonora Grandi · Davis, California
Research Focus
Dr. Eleonora Grandi's lab at UC Davis focuses on understanding how atrial fibrillation (AF) affects men and women differently. This research is crucial because women often have worse symptoms and outcomes from AF. The lab uses advanced computational models and experimental techniques to analyze how sex hormones influence heart cell function and arrhythmia risk. Ultimately, the lab aims to develop better treatments that account for these differences.
atrial fibrillationsex-specific researchcomputational modelingelectrophysiologyion channelshormonal effectsanti-arrhythmia therapiescalcium handlingcardiac research
Research Aims
3AIM 01Develop sex-specific computational models of human atrial myocytes.
AIM 02Investigate the role of sex hormones in atrial electrophysiology and arrhythmia risk.
AIM 03Identify new anti-AF strategies targeting sex-specific mechanisms.
Skills the Lab Values
computational modelingoptical mappingcell cultureelectrophysiology techniquesdata analysisexperimental designpharmaceutical testinganimal modelssoftware simulations
Output against the department
Publications206top 43% of dept.198th of 462
this lab
most publishedleast published
Citations5.3kbottom 39% of dept.282nd of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.