Yale University · BiochemistryHatzios Lab
Stavroula Hatzios · New Haven, Connecticut
Research Focus
Dr. Stavroula Hatzios's lab at Yale University conducts research on how microbial infections contribute to cancer development. By focusing on oxidative stress, which is often caused by infections, they study how specific sites on proteins are modified and impact cellular functions. The lab utilizes innovative techniques to uncover these modifications, aiming to establish new therapeutic strategies to combat cancer linked to infections.
oxidative stresscancerinfectionchemoproteomicsproteomicscysteine oxidationHelicobacter pyloritumorigenesis
Research Aims
3AIM 01Define the molecular mechanisms linking Cys219 inactivation to legumain processing and trafficking.
AIM 02Establish whether oxidation of the ribosomal protein uL14 inhibits translation.
AIM 03Functionally map novel sites of cysteine oxidation induced by bacterial proteins in vivo.
Skills the Lab Values
chemical proteomicsmass spectrometrycell culturemouse modelsmetabolic labelingquantitative proteomicswestern blottingimmunoprecipitationRNA sequencing
Output against the department
Publications43bottom 6% of dept.378th of 402
this lab
most publishedleast published
Citations8.0kbottom 43% of dept.229th of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.