Florida International University · Microbiology & ImmunologyThe Lung Health Initiative
Hoshang Jehangir Unwalla · Miami, Florida
Research Focus
Dr. Hoshang Unwalla's lab focuses on understanding how HIV affects the lungs, particularly in people living with HIV who develop COPD. The team explores the role of microRNAs and the lung's molecular clock in this process, aiming to find new ways to prevent and treat COPD in these individuals. Their work combines cutting-edge techniques, like CRISPR, to manipulate gene expression and address the unique challenges posed by HIV in lung health.
HIVCOPDmicroRNAslung inflammationCRISPR
Research Aims
3AIM 01Identify how HIV and TGF- signaling affect the airway microRNAome and contribute to COPD.
AIM 02Investigate the dysregulation of the lung molecular clock due to HIV Tat protein.
AIM 03Develop strategies to reset the lung molecular clock and reduce inflammation in HIV-affected individuals.
Skills the Lab Values
gene editing (CRISPR)cell culturemolecular clock analysisRNA extractionqPCR
Output against the department
Publications78bottom 25% of dept.362nd of 486
this lab
most publishedleast published
Citations1.2kbottom 7% of dept.454th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.