University of California-Berkeley · ChemistryInnovative Catalysis and Medicinal Chemistry Lab
John F Hartwig · Berkeley, California
Research Focus
Professor John F. Hartwig's lab at UC Berkeley focuses on developing innovative chemical reactions that are essential for creating new medications. The lab works with transition metals to discover new catalysts that can streamline the production of important organic compounds, particularly those that target specific parts of complex molecules. This research aims to deepen our understanding of how these catalysts operate, leading to more effective and efficient synthetic methods in medicinal chemistry.
Organic SynthesisMedicinal ChemistryTransition MetalsCatalystsChemical ReactionsC-H FunctionalizationCross CouplingMetalloenzymesStereoselectivity
Research Aims
5AIM 01Discover new organic reactions that can be catalyzed by transition metals.
AIM 02Develop catalysts that allow selective functionalization of C-H bonds.
AIM 03Create methods for synthesizing complex organic molecules efficiently.
AIM 04Investigate the mechanistic pathways of chemical reactions in medicinal chemistry.
AIM 05Enhance the understanding of artificial metalloenzymes for targeted synthesis.
Skills the Lab Values
Organic synthesis techniquesCatalyst design and evaluationMechanistic studiesKinetic analysisUse of transition metal complexesFunctional group modificationStereochemical controlDrug development methodologiesLaboratory safety practices
Output against the department
Publications1,115top 3% of dept.7th of 216
this lab
most publishedleast published
Citations95ktop 1% of dept.2nd of 216
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.