Texas A&M University-College Station · GeneticsHuang Lab
Yun Huang · College Station, Texas
Research Focus
Dr. Yun Huang's lab at Texas A&M University focuses on understanding how epigenetic factors regulate heart development. The team investigates how specific genetic mutations and maternal diet can impact heart formation and contribute to congenital heart diseases. They use cutting-edge techniques with genetically modified mouse models and human stem cells to explore these mechanisms and seek ways to improve heart development and health.
epigeneticsheart developmentcongenital heart diseasesmetabolic stressTET proteinsstem cellscardiovascular healthDNA methylationenhancer regulationlipid metabolism
Research Aims
3AIM 01Investigate how TET2 mutations affect heart development in congenital heart disease
AIM 02Unravel mechanisms of TET-mediated enhancer recognition during heart formation
AIM 03Examine the impact of a high-fat maternal diet on TET-related epigenetic regulation
Skills the Lab Values
genetically modified mouse modelshuman embryonic stem cell differentiationepigenetic analysisgene expression studiesmolecular biology techniquescell culturechromatin accessibility assaysRNA sequencingPCRWestern blot
Output against the department
Publications234top 36% of dept.93rd of 259
this lab
most publishedleast published
Citations14ktop 41% of dept.105th of 259
this lab
most citedleast cited
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