Columbia University in the City of New York · Biomedical EngineeringThe Radiomics Initiative
Despina Kontos · New York, New York
Research Focus
Dr. Despina Kontos leads a research lab focused on improving cancer treatment for patients with non-small cell lung cancer, particularly through the development of new diagnostic tools. The lab investigates how to use advanced imaging techniques to better understand tumor characteristics and predict patient responses to immunotherapy. By combining radiomic signatures with established biomarkers, the lab aims to enhance patient stratification and clinical outcomes in cancer management.
radiomicsnon-small cell lung cancerimmunotherapyPDL1dose-response predictionbiomarkersCT imagingcancer diagnosticstumor heterogeneityclinical validation
Research Aims
5AIM 01Identify radiomic signatures that predict response to immunotherapy in NSCLC patients.
AIM 02Evaluate how radiomic signatures can enhance established biomarkers like PDL1 expression.
AIM 03Correlate radiomic features with clinical outcomes such as progression-free survival.
AIM 04Conduct the largest radiomics study on NSCLC immunotherapy using a comprehensive patient database.
AIM 05Develop an integrated-diagnostics tool for better clinical decision-making in cancer treatment.
Skills the Lab Values
CT image analysisradiomic feature extractiondata miningclinical trial designbiostatisticsbiomarker evaluationmachine learningsoftware utilization (CapTK)longitudinal patient data analysispatient database management
Output against the department
Publications326top 29% of dept.170th of 595
this lab
most publishedleast published
Citations5.6kbottom 43% of dept.339th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.